Cell patterning is a method to induce cells to selectively adhere to the designed area through their own response mechanism by preparing a certain patterned substrate. This technology can simulate the microenvironment in vivo, accurately locate cells in specific positions, control the morphology and number of cells, simplify the research process, and facilitate the detection of cell response to external environment and external signals.
Wu, Cong et al.(2018). Lab on a chip, 18 20, 3074-3078.
In vivo, cell microenvironment has a crucial impact on the regulation of cell behavior and function. Therefore, one of the challenges cell biologists facing is to use a controllable and repeatable microenvironment to study cells and model diseases more effectively.
Cell patterning is the key to solve this challenge!
We chemically modified cell adhesion molecules or anti-cell adhesion molecules on the basal surface to construct cytophilic and acellular regions for selective cell adhesion; we can also construct physical barriers by physical means to limit cell growth and form specific cell patterns.
We deposit cells on the substrate surface by means of light assistance, electrical stimulation, mechanical load and direct printing to form accurate cell micropatterns.
Accurately simulate the microenvironment in vivo to obtain a more reliable and repeatable physiological model in vitro.
Cell culture and cell biological detection, which cannot be realized by traditional culture, can be solved by cell patterning technology.
Overcome the shortcomings of traditional cell analysis, accurately summarize human diseases or capture the role of drugs, and provide better accuracy in drug discovery.
Creative Bioarray, as a biotechnology development company, can design the most suitable cell model for you with comprehensive expertise. By mastering the key parameters of the cell model and appropriate culture conditions, we can develop more physiological-related models. We are committed to enabling our customers to benefit from our expertise to meet their needs for cell- and drug-based detection development.
Welcome to contact us for cooperation, we are honored to be your competent research assistant.