Creative Bioarray can help you realize the micro-scale patterning of surface nerve cells, simulate the internal environment of central nerve, control the growth of neuron cells according to the patterned path, so as to form a specific neural network, analyze ions in nerve cells, and quantify nerve cell axons. We aim to provide new tools for neurobiology research and accelerate your research process in this field.

Single-cell Patterning for Analyze Ions in Nerve Cells

In the nervous system, various metal ions are interrelated and play a vital role. Overload and deficiency of metal ions will lead to a series of neurodegenerative diseases. Therefore, the detection of various metal ions in the nervous system is very important for the basic research and clinical detection of nervous system diseases.

However, the current metal ion detection methods based on a large number of cell samples will make the heterogeneity of individual cells and the accurate correlation between multiple metal ions masked by the average data of population cells. Single cell patterning technology can capture and locate single cells in space. Combined with electrophoresis technology, it can effectively separate and detect intracellular metal ions, which is of great significance to reveal the mechanism of nervous system diseases.

Microfluidic Cell Patterning for Controlling the Growth and Differentiation of Nerve Cells

The study of nerve cells growth plays an important role in nerve development and synaptic function reconstruction after injury. Our cell patterning technology is an important method to simulate the internal environment of central nervous system. Among them, the cell patterning technology in the microfluidic device can control the cell proportion and imitate the extracellular matrix, and simulate the in vivo environment of various nervous system diseases.

In our patterned microfluidic channel, metabolites have a certain degree of diffusion and communication, produce a local microenvironment with chemical concentration gradient, and induce the growth and differentiation of nerve cells in varying degrees. Our cell patterning technology can help you understand and study the morphological information of nerve cells and the influence of spatial structure on the growth of cells on the micron or even nano scale, and help you grow neuron cells according to the patterned path to form a specific neural network.

Microfluidic Cell Patterning for Quantifying Nerve Cell Axons

Central nervous system neuronal axon injury is very important for the etiology of neurodegenerative diseases and central nervous system injury. Animal models involve many parameters, so they can't monitor axon damage or regeneration in real time. Traditional methods can't distinguish the different growth forms of normal and injured regenerated neurons, and lack of appropriate methods to induce axonal injury in an accurate and controlled way.

Our cell patterning technology allows guiding axon growth, separating axons and quantifying neurons. Cell patterning technology can reconstruct nerve cell tissue, reduce the gap between in vivo and in vitro simulation, and enable neurons to express axon markers tubulin. Cell patterning technology in the microfluidic device can also separate the neuron cell body from its axon, which is conducive to collecting a large number of axon tissue materials with high purity for quantitative analysis.

Get in Touch

Creative Bioarray provides customers with cell patterning customization and related detection services based on Cell Patterning, you can contact our employees directly to ask questions if you are interested in our services, please contact us for more details.