Through cell patterning technology, Creative Bioarray can accurately simulate the extracellular environment and flexibly adjust the drug concentration, use its special fluid properties to determine the potential concentration and combination of a variety of reagents, and test the activity of combined drugs with different concentrations. This method is suitable for high-content screening and high-throughput screening, and helps you find the best drug combination as soon as possible.

Why Cell Patterning for Optimal Combinatorial Drug Screening?

In clinical treatment, the combined use of two or more drugs may improve the effect of fighting some diseases. Therefore, it is of great significance to study the efficient and optimal combination drug screening under different drug concentrations. However, due to the increasingly serious ethical problems, the use of animal experiments in drug screening and development is decreasing. As an alternative, human derived cells are commonly used for in vitro testing, but this method has many disadvantages, such as time-consuming, unable to accurately simulate the cell microenvironment and unable to represent the real reflection in the human body.

Our microfluidic cell patterning technology can accurately simulate the extracellular environment and flexibly adjust the drug concentration, use its special fluid properties to determine the potential concentration and combination of a variety of reagents, and allow easy continuous dilution of drugs, which is helpful to monitor the dose response of drugs.

Advantages

Firstly, our microfluidic cell patterning technology provides an ideal controlled environment for cell culture and drug testing, including a variety of cells such as cancer, liver and bacteria. This controlled environment allows long-term monitoring of cell culture, and can provide an environment with high similarity with the body, so as to generate more accurate data and improve the efficiency of drug testing.

Secondly, our microfluidic cell patterning technology has many advantages in controlling the concentration gradient of drugs. For example, it can produce a wider concentration range and divide the concentration gradient more finely in space; gradient environment is more stable and can be monitored in real time; the concentration gradient can change dynamically over time to meet different needs.

Finally, several different concentrations of drugs can be used as input in the device composed of isolated cell culture chamber. In the microfluidic cell patterning device, a variety of different cellular drug reactions can be screened, which not only reduces the cost, but also improves the time efficiency of detection.

What Can We Do?

Biopatterning, as an advanced technology platform for cell patterning, can provide appropriate in vitro model establishment and multi-endpoint testing and analysis services. Our cell patterning technology can not only closely simulate the extracellular environment, but also flexibly adjust the drug concentration. Through this technology, we can provide an ideal controlled environment for your drug test, allow the drug to be tested in a microenvironment similar to the body, and provide you with more reliable data.

In addition, the microfluidic cell patterned device we developed can implement the potential concentration and combination of a variety of reagents, and accurately manipulate different concentrations of drugs into the cell chamber to screen a variety of different cell drug reactions. Our advantage is that we can use a highly integrated microfluidic cell patterning device to test the activity of different concentrations of combination drugs. The device is suitable for high-content screening and high-throughput screening, which helps you find the best drug combination as soon as possible.

Why Choose Us?

• Low consumption of compounds
• High repeatability of results
• High screening efficiency
• Quantifiable readings with vitality indicators
• Scientific and reasonable scheme design

Creative Bioarray provides customers with cell patterning customization and related detection services based on Cell Patterning, you can contact our employees directly to ask questions if you are interested in our services, please contact us for more details.