Based on Cell Patterning, Creative Bioarray can use cell patterning technology to help you establish functional in vitro neural tissues. The development of neural tissues model provides an important opportunity to simulate human nervous system diseases. In addition, this new in vitro model provides a powerful tool for you to study the potential pathogenesis of nervous system diseases, which can be used to clarify the molecular drivers of various neurological diseases or as a high-throughput drug screening platform.

Fig.1 3D Bioprinting of Neural Tissues. (Chen C, et al.,1997)

Applications of Cell Patterning for Neural Tissues

Nervous system damage leads to the interruption of neural networks and information transmission throughout the body. Our cell patterning technology enables you to better understand the development of neural tissues and their related diseases, because the 3D neural tissues established by this technology can more closely simulate the natural extracellular microenvironment, spatial distribution, function or functional disorder of cells. The model is of great significance in the modeling of nervous systems, because it can not only promote the pathological research of nervous systems and diseases, but also accelerate the development of potential therapeutic approaches for neurodevelopmental mental disorders and neurodegenerative diseases.

What Can We Do?

Our in vitro neural tissues are manufactured by cell patterning technology of 3D bioprinting, which is mainly divided into three categories: extrusion, droplet and laser bioprinting. Our technology can provide the ability to organize neuronal groups in 3D by layer deposition, so as to reproduce the complexity of active neural tissue and provide you with neural tissues with higher repeatability, accuracy and relevance.

Our 3D printing technology is a powerful tool for constructing bioengineering neural tissue structure. Compared with traditional models, our 3D printing technology provides a higher degree of freedom for the development of neural tissue in vitro, and can effectively replicate the whole range of nervous system disease pathology. Our controlled patterning of cells, materials and biomolecular factors can build complex and repeatable structures for you. This technology provides a useful alternative method for studying the potential pathogenesis of human nervous system diseases, which can be used to clarify the molecular drivers of various neurological diseases or as a high-throughput drug screening platform. Specifically, we can provide you with the following services:

• Vascularized nerve tissue
• Brain organoids
• Incorporation of nerve cells into other tissue scaffolds to promote regeneration
• Neurodegenerative disease modeling (Glioblastoma, Alzheimer's disease, Parkinson's disease)

Why Choose Us?

• High cell viability
• Reproduce the complexity of active tissue
• Scientific and reasonable scheme design
• Rich experience in cell patterning projects
• High quality and fast service

Creative Bioarray provides customers with cell patterning customization and related detection services based on Cell Patterning, you can contact our employees directly to ask questions if you are interested in our services, please contact us for more details.

Reference:

1. Chen C.; et al. Geometric Control of Cell Life and Death. Science. 1997, 276(5317):1425-1428